DSpace Repository

National University - Sudan(NUSU) Repository

National University - Sudan(NUSU) Repository

Recent Submissions

  • Koko, Mahmoud; Yahia, Ashraf; Elsayed, Liena E; Hamed, Ahlam A; Mohammed, Inaam N; Elseed, Maha A; Hamad, Muddathir H A; Babai, Arwa M; Siddig, Rayan A; Abd Allah, Amal S I; Mohamed, Mayada; El-Amin, Melka; Esteves, Typhaine; Altmüller, Janine; Toliat, Mohammad Reza; Thiele, Holger; Nürnberg, Peter; Ahmed, Ammar E; Salih, Mustafa A; Stevanin, Giovanni (Ann Hum Genet ., 2021)
    PRUNE1 is linked to a wide range of neurodevelopmental and neurodegenerative phenotypes. Multiple pathogenic missense and stop-gain PRUNE1 variants were identified in its DHH and DHHA2 phosphodiesterase domains. Conversely, ...
  • Yahia, Ashraf; Elsayed, Liena E. O.; Valter, Remi; Hamed, Ahlam A. A.; Mohammed, Inaam N.; Elseed, Maha A.; Salih, Mustafa A.; Esteves, Typhaine; Auger, Nicolas; Abubaker, Rayan; Koko, Mahmoud; Abozar, Fatima; Malik, Hiba; Adil, Rawaa; Emad, Sara; Musallam, Mhammed Alhassan; Idris, Razaz; Eltazi, Isra Z. M.; Babai, Arwa; Ahmed, Elhami A. A.; Abd Allah, Amal S. I.; Mairey, Mathilde; Ahmed, Ahmed K. M. A.; Elbashir, Mustafa I.; Brice, Alexis; Ibrahim, Muntaser E.; Ahmed, Ammar E.; Lamari, Foudil; Stevanin, Giovanni (Frontiers in Neurology, 2021)
    Introduction: Hereditary spastic paraplegia is a clinically and genetically heterogeneous neurological entity that includes more than 80 disorders which share lower limb spasticity as a common feature. Abnormalities in ...
  • Mokhtar, Ahmed E.; Mustafa, Wegdan M.; Ali, Qurashi (The FASEB Journal, 2014)
    Ultrasonic measurement of fetal Femur Length(FL) and Bi-Partial Diameter(BPL) is a precise tool for estimation of fetal growth and development. Accurate estimation of gestational age is vital for efficient obstetric planning ...
  • Ahmed, Wegdan; Osman, Tahir; Sahin, Bunyamin; Elfaki, Amani (Journal of Experimental and Clinical Medicine, 2021)
    Grey matter (GM) of the frontal lobe carries out its complex function such as muscle control, speech, decision making, and self-control; while the white matter (WM) of frontal lobe is a major contributor to human brain ...
  • Mohammed, Sarah Suliman; Mohammed, Mohammed Elfadil; Hegazi, Amal Sami; Ali, Malaz Mohammed (IOSR Journal of Dental and Medical Sciences (IOSR-JDMS), 2021)
    Background: The lesions that affect white matter of the brain could be duo to a variety of causes this study discusses the inflammatory, demyelinating, tumors and lesions found in normal ageing process. The main concept ...
  • Cauley, Edmund S; Hamed, Ahlam; Mohamed, Inaam N.; Elseed, Maha; Martinez, Samantha; Yahia, Ashraf; Abozar, Fatima; Abubakr, Rayan; Koko, Mahmoud; Elsayed, Liena; Piao, Xianhua; Salih, Mustafa A.; Manzini, M Chiara (Neurogenetics, 2019)
    Genetic mutations associated with brain malformations can lead to a spectrum of severity and it is often difficult to determine whether there are additional pathogenic variants contributing to the phenotype. Here, we present ...
  • Yahia, Ashraf; Chen, Zhefan Stephen; Ahmed, Ammar E.; Emad, Sara; Adil, Rawaa; Abubaker, Rayan; Taha, Shaimaa Omer M. A.; Salih, Mustafa A.; Elsayed, Liena; Chan, Ho Yin Edwin; Stevanin, Giovanni (BMC Neurology, 2021)
    Background: CCDC88C is a ubiquitously expressed protein with multiple functions, including roles in cell polarity and the development of dendrites in the nervous system. Bi-allelic mutations in the CCDC88C gene cause autosomal ...
  • Elsayed, Liena E. O.; Mohammed, Inaam N.; Hamed, Ahlam A. A; Elseed, Maha A.; Salih, Mustafa A. M.; Yahia, Ashraf; Abubaker, Rayan; Koko, Mahmoud; Abd Allah, Amal S. I.; Elbashir, Mustafa I; Ibrahim, Muntaser E.; Brice, Alexis; Ahmed, Ammar E.; Stevanin, Giovanni (Frontiers in Neurology, 2020)
    Background: Arginases catalyze the last step in the urea cycle. Hyperargininemia, a rare autosomal-recessive disorder of the urea cycle, presents after the first year of age with regression of milestones and evolves ...
  • Yahia, Ashraf; Stevanin, Giovanni (Frontiers in Genetics, 2021)
    Hereditary spinocerebellar degeneration (SCD) encompasses an expanding list of rare diseases with a broad clinical and genetic heterogeneity, complicating their diagnosis and management in daily clinical practice. Correct ...
  • Seed Ahmed, Mohammed Hamza Z. E (Karolinska Institutet, 2013)
    Type 2 diabetes (T2D) and obesity are highly prevalent disorders reflecting a complex interplay of genetics, epigenetics, and environment. They constitute serious health problems and lead to significant morbidity and ...
  • Seed Ahmed, Mohammed; Kovoor, Abraham; Nordman, Sofia; Abu Seman, Norhashimah; Gu, Tianwei; Efendic, Suad; Brismar, Kerstin; Östenson, Claes-Göran; Gu, Harvest F. (Islets, 2012)
    Adenylyl cyclase 3 (AC3) is expressed in pancreatic islets of the Goto-Kakizaki (GK) rat, a spontaneous animal model of type 2 diabetes (T2D), and also exerts genetic effects on the regulation of body weight in man. In ...
  • Hasan, Noaman M.; Longacre, Melissa J.; Seed Ahmed, Mohammed; Kendrick, Mindy A.; Gu, Harvest; Ostenson, Claes-Goran; Fukao, Toshiyuki; MacDonald, Michael J. (Archives of Biochemistry and Biophysics, 2010)
    Succinyl-CoA:3-ketoacid-CoA transferase (SCOT) is a mitochondrial enzyme that catalyzes the reversible transfer of coenzyme-A from acetoacetyl-CoA to succinate to form acetoacetate and succinyl-CoA. mRNAs of SCOT and ATP ...
  • Tajeddinn, Walid; Persson, Torbjorn; Calvo-Garrido, Javier; Seed Ahmed, Mohammed; Maioli, Silvia; Vijayaraghavan, Swetha; Kazokoglu, Mehmet Selim; Parrado-Fernandez, Cristina; Yoshitake, Takashi; Kehr, Jan; Francis, Paul; Winblad, Bengt; Hoglund, Kina; Cedazo-Minguez, Angel; Aarsland, Dag (Journal of Alzheimer’s Disease, 2016)
    Serotonin (5-HT) plays a central role in the integrity of different brain functions. The 5-HT homeostasis is regulated by many factors, including serotonin transporter (SERT), monoamine oxidase enzyme (MAO), and several ...
  • Haytural, Hazal; Lundgren, Jolanta L; Kose, Tansu B; Jordà-Siquier, Tomàs; Kalcheva, Marinela; Seed Ahmed, Mohammed; Winblad, Bengt; Sundström, Erik; Barthet, Gael; Tjernberg, Lars O.; Frykman, Susanne (Frontiers, 2019)
    The use of human post-mortem brain material is of great value when investigating which pathological mechanisms occur in human brain, and to avoid translational problems which have for example been evident when translating ...
  • Charani, Esmita; Cunnington, Aubrey J; Yousif, AlaEldin H A; Seed Ahmed, Mohammed; Ahmed, Ammar E M; Babiker, Souad; Badri, Shahinaz; Buytaert, Wouter; Crawford, Michael A; Elbashir, Mustafa I; Elhag, Kamal; Elsiddig, Kamal E; Hakim, Nadey; Johnson, Mark R; Miras, Alexander D; Swar, Mohamed O; Templeton, Michael R; Taylor-Robinson, Simon David (BMJ Global Health, 2019)
    A recent symposium and workshop in Khartoum, the capital of the Republic of Sudan, brought together broad expertise from three universities to address the current burden of communicable and non-communicable diseases ...
  • La˚ ngberg, Ewa-Carin; Seed Ahmed, Mohammed; Efendic, Suad; Gu, Harvest F.; Ostenson, Claes-Goran (Obesity, 2013)
    Objective: The sympathetic nervous system (SNS) is linked to glucose, lipid, and protein metabolism. The a2A-adrenergic receptor (ADRA2A) is involved in the SNS and mediates inhibition of insulin secretion and lipolysis. ...
  • Seed Ahmed, Mohammed; Pelletier, Julien; Leumann, Hannes; Gu, Harvest F.; Östenson, Claes-Göran (PLOS ONE, 2015)
    Protein kinase C (PKC) is a family of protein kinases controlling protein phosphorylation and playing important roles in the regulation of metabolism. We have investigated expression levels of PKC isoforms in pancreatic ...
  • Tajeddinn, Walid; Fereshtehnejad, Seyed-Mohammad; Seed Ahmed, Mohammed; Yoshitake, Takashi; Kehr, Jan; Shahnaz, Tasmin; Milovanovic, Micha; Behbahani, Homira; Hoglund, Kina; Winblad, Bengt; Cedazo-Minguez, Angel; Jelic, Vesna; Jaremo, Petter; Aarsland, Dag (Journal of Alzheimer’s Disease, 2016)
    Introduction: Serotonin (5-HT) is involved in the pathology of Alzheimer’s disease (AD). Objective: We aimed to measure 5-HT level in platelets in AD and explore its association with cerebrospinal fluid (CSF), AD biomarkers ...
  • Wu, L.; Shen, C.; Seed Ahmed, M.; Östenson, C.-G.; Gu, H. F. (obesity reviews, 2016)
    Obesity has become epidemic worldwide, and abdominal obesity has a negative im- pact on health. Current treatment options on obesity, however, still remain limited. It is then of importance to find a new target for ...
  • Hamid, Wissam S; Ahmed, Humeda S; Osman, Mona A; Babiker, Rasha (Journal of Endocrinology, Metabolism and Diabetes of South Africa, 2021)
    Background: Diabetic neuropathy is one of the most common microvascular complications associated with diabetes mellitus. Diabetic peripheral neuropathy (DPN) has been linked to hyperglycaemia and long duration of uncontrolled ...

View more